Psilocybin Therapy

Exploring potential routes away from Treatment Resistant Depression

Psilocybin Therapy is currently being explored as a potenial new route away from depression.  Psilocybin Therapy is not approved by any regulatory agency in California and is currently only available in clinical trials. The safety and efficacy of psilocybin therapy have not yet been established for the treatment of treatment resistant depression.

The California Center for Psychedelic Therapy currently hosts a psilocybin clinical trial. Many people who receive antidepressant treatment for their depression do not get an adequate response to the medicines they are taking. If someone is taking two or more antidepressants and they are failing, this is sometimes referred to as treatment-resistant depression or TRD.

Our study is looking into a new treatment approach for people with TRD using an investigational medicine given with psychological support. The study is suitable for people who have been diagnosed with major depression and are currently experiencing a recurrent or single episode of depression but that have not responded to antidepressant treatment.

Who is eligable to participate in the COMP 005 Study?

You may be eligible if you meet the following criteria:

• Are 18 years of age or older

• Have been diagnosed with major depression (single or recurrent episodes)

• Are experiencing treatment-resistant depression, defined as failing 2, 3, or 4 pharmacological treatments for your current episode of depression

• Meet additional study criteria (please see the clinialtrails.gov website for more information)

Where does the treatment take place?

The California Center for Psychedelic Therapy's Larchmont location is a participating study site, but there are others throughout California an the United States. 

How can I learn more?

If you are interested in learning more about the COMP005 study, please reach out to one of the contacts listed on the clinicaltrials.gov website. 

Expressing an interest does not oblige you in any way to take part in the study.